With GenNext_klinik, you can perform data processing, annotation, and variant filtering starting from a FASTQ, BAM, or VCF file, and form a report with the selected variant(s) using our automatic reporting tool.

Due to GenNext_klinik‘s streamlined user-friendly interface, you can save the options you use most frequently in your analysis for the next time. You can view your saved analysis and filtering options and customize them as you wish.

The platform offers duo and trio case filtering options in addition to both predefined and customizable filtering options -including clinical, research, and specialized- to facilitate your analyses. GenNext_klinik offers over 150 up-to-date annotators, HPO (Human Phenotype Ontology)-integrated gene listing options that can be saved within your account. It also offers a CNV filtering tool to perform case-specific analysis for your clinical, research, and challenging cases suitable for routine diagnostics.

GenNext_klinik is suitable for the analysis of both germline and somatic variants. Due to the integrated system of the platform, the variant can be visualized and validated using the BAM file simultaneously during the variant filtering step, and if necessary, it can be displayed and analyzed together with RNA sequencing data.