Gennext Clinical

Clinical Genomics Platform

In Clinical Genetic Analyses, Powerful, Fast and Reliable Solution.

Gennext Clinic is a clinical decision support platform that accelerates high-accuracy genetic analysis, phenotype matching, and interpretation processes for rare and inherited diseases.

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We transform complex genetic data into meaningful insights.

Medical Genetics Specialists
Pediatric Geneticists
Pathologists and Oncologists
University Hospitals
Private Hospitals
Clinical Laboratories
Accelerates time-consuming analysis workflows in clinical settings
Reduces variant analysis and interpretation timelines from weeks to days.
GPU-accelerated variant analysis infrastructure
Delivers high accuracy and reproducibility with GATK/DRAGEN-compatible pipelines.
Secure data processing compliant with data protection regulations
Thanks to a federated data model, sequencing data never leaves the institution.

Clinical Use Cases

Rare / Inherited Diseases

Advanced modules that simplify the analysis of genetically driven disorders in pediatric and adult patients.

HPO (Human Phenotype Ontology)-supported variant prioritization
Pathogenicity classification according to ACMG (American College of Medical Genetics and Genomics) and AMP (Association for Molecular Pathology) standards
Trio and segregation analysis
University Hospitals
CNV / SNV / Indel detection
Clinically compliant PDF/JSON reports
Sample Report
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Sample Report
Oncology

Analyses that support treatment decisions through tumor profiling and actionable gene sets.

Tumor mutation profiling
Actionable variant detection
FDA, ESMO, NCCN compliant
TMB, MSI and HRD calculations supported
Clinical decision support report (PDF/JSON)
Clinically compliant PDF/JSON reports
Sample Report
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Sample Report

How It Works?

Validation & Evidence

Data Security

Gennext Clinical is a genomic analysis platform designed for rare diseases, cancer, and other genetic disorders, focusing on variant analysis, interpretation, and clinical reporting of post-sequencing data (VCF/BAM/FASTQ).

Rare and complex genetic diseases
Hereditary cancer syndromes
Somatic tumor panels and WES/WGS-based analyses
Carrier screening and family studies

It is a bioinformatics and clinical reporting platform. It does not perform wet-lab procedures and works with sequencing data generated by partner or in-house NGS laboratories.

Targeted gene panels (germline/somatic)
Whole Exome Sequencing (WES)
Whole Genome Sequencing (WGS)
CNV analysis for selected panels
VCF (preferred)
BAM/CRAM
FASTQ (on request)
Test definition and clinical indication
Sequencing at partner or in-house lab
Secure data transfer
Automated analysis and QC
ACMG-based variant classification
Clinical review and reporting
ACMG/AMP for germline variants
AMP/ASCO/CAP and ESMO for somatic variants
Clinical summary and indication
Test and technical overview
Clinically relevant variants
Variant classification and evidence
Clinical recommendations

Common benign variants or incidental findings unrelated to the clinical indication may be excluded or summarized separately, in line with institutional and ethical policies.

Evidence is clearly reported
Follow-up testing may be recommended
Not used alone for diagnosis

Data is stored on encrypted, access-controlled infrastructure compliant with KVKK and, where applicable, GDPR.

The patient is the data owner. Deletion or anonymization requests are handled according to legal regulations.

Only with explicit consent and ethical approval, using the highest possible anonymization level.

Depends on test type, case volume, and scope, and is defined via SLA agreements.

Pricing is typically per test, per case, or via institutional licensing models.

Reports include responsible experts and technical or scientific contact details.

Yes. HL7, FHIR, REST API, and CSV/TSV-based integrations are supported.

Yes, provided quality metrics are met and security requirements are defined.

Optional re-analysis is available using updated databases, literature, and algorithms.

    Accelerate your diagnostic workflows with Gennext Clinic.

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